Reproduction management is to have cows become pregnant at a biologically optimal time and at an economically profitable interval after calving. The timing of examination of animals after parturition should allow for the normal process of involution, yet also provide sufficient time for treatment and response prior to the start of the breeding period. The aims of uterine disease treatments are to reverse inflammatory changes that impair fertility, whilst enhancing uterine defence and repair.

The implication of this study suggests of recuperate the cows with reproductive problems of infertility. For this will be monitor incidence of disease that induced infertility, will made diagnose and discovered a new therapy for pathology resolution. After a first phase of epidemiology investigation and diagnose of viral and bacterial disease more present on Teramo territory, will be made in vitro and in vivo experiments for evaluate efficiency of ozono therapy.

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